Lying of Hands DEMONSLAYING

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The following things do not work with Smite:

- Leech (life/mana)
- Deadly Strike/Critical Strike (confirmed by both Oramin and Vash-dm independently in 1.11)
- Knockback (apart from the standard Knockback on the skill)
- Elemental damage from equipment or charms
- Elemental damage from auras (e.g. Holy Shock) (the area effect will still work, just not the applied damage)
- Poison damage from charms or the Venom proc on "Treachery"
- Magic damage from Sanctuary (note that I havent verified this for 1.10+ but I dont see any reason it should have changed; the area effect will still work, just not the applied damage) (added on behalf of gibbousmoon)
- Gear and charms that add a set amount of damage (verified by SSJPunk) except for those items which have the Damage +X attribute (e.g. WarTravs will *not* add damage to Smite except for the STR bonus)
- Enhanced Damage on the weapon
- Enhanced Damage to Demons (e.g. Laying of Hands) (Thanks to Bonkshasa and Posterboy for testing)
- Enhanced Damage to Undead has *not* been tested, but it should behave the same way as Enhanced Damage to Demons


Taken from here
General Smiter FAQ - Diablo 2 @ Diablo2.com Forums